High efficiency COMPACT Preparative Chromatography System.

• 4 Channel 
• Scanning 
• 200-800
• 250 ml/min
• 4,351 psi

System includes:

• UV-Vis DAD detector 
• Preparative gradient pump
• Automatic injection valve
• Fraction collector 

The FLASH 250 Detector 

• Measures four (4) wavelengths simultaneously 
• Spectral scanning 
• Can handle 10-50 millimeter diameter ID columns 

Flash Chromatography is a purification technique not an analytical tool like HPLC or UHPLC. Flash has been around for decades and was primarily used for pharmaceutical drug discovery R & D. Flash chromatography was used when a medicinal or organic chemist synthesized a new drug molecule. Before the chemist could study the compound of interest, they needed to purify or “clean up” the compound. The crude reaction mixture passes through a flash chromatography column in a “flash”. The pure drug compound is then isolated by selective elution. Flash Chromatography is a very effective purification technique and is still considered the primary purification technique used in R & D for the Pharmaceutical industry today.

Flash Chromatography is a type of preparative liquid chromatography. Flash Chromatography may be referred to as column chromatography or medium pressure Chromatography. Flash Chromatography is a special type of column chromatography. The FLASH 50 and FLASH 250 are capable of doing both preparative Flash Chromatography and preparative HPLC on the same system. Flash Chromatography is a preparative liquid chromatography method that easily and quickly separates organic compounds.

In chemistry, column chromatography is a chromatography method that is used to isolate a single chemical compound from a mixture. Flash Chromatography does just that, it purifies individual chemical compounds from a mixture of compounds. Flash Chromatography is most commonly used in the pharmaceutical industry for drug discovery, peptide and antibiotic purification, sample clean-up, early stage drug discovery, protein analysis, natural product analysis and more recently cannabis and hemp analysis.

Column chromatography techniques are implemented to separate steroids, hormones, vitamins alkaloids, cannabis and hemp. Column chromatography is also used to determine the amounts of those substances in samples of body fluids. Therefore, Flash Chromatography is an efficient method of extracting and purifying cannabis and hemp. There is an overwhelming need for a higher purity products. These techniques isolate cannabinoids and can further purify extracted cannabis raw materials.

Even though Flash Chromatography is a “medium pressure chromatography” both the FLASH 50 and the FLASH 250 systems can handle up to 4,351 psi. Flash Chromatography is a rapid method of column chromatography. It is called “flash” because it is a rapid method of column chromatography. Flash chromatography is high resolution chromatography. The solvent is pumped through a packed column at high flow rates. The sample loading capacity impacts yield and purity. While higher loads improve yield, they may diminish purity and lower loads may improve purity but possibly reduce yield.

Flash Chromatography is a very successful technique for those needing to purify cannabis and hemp extracts in order to remove impurities and isolate or separate individual cannabinoids. Flash Chromatography is also being used to isolate and purify cannabinoids for use in edible products.

An automated purification system includes a UV/VIS DAD Detector, a preparative gradient pump, automatic injection valve and a fraction collector. All of these components are controlled by a touch panel. There are two Flash Chromatography modes, normal-phase and reverse-phase. The phases have different separation mechanisms depending on your purification goals. Normal phase works well when separating compounds with significantly different polarities. It is often used to remove unwanted co-extractants and polar co-extracted impurities.

Flash Chromatography can be used as the front end of a CPC (Centrifugal Partition Chromatography) system. The cannabis and hemp processing industry needs to purify cannabis and hemp extracts in order to remove impurities an isolate/ separate individual cannabinoids. Flash Chromatography is one of the most successful methods used to achieve accurate, fast results. Icon Scientific offers many solutions to improve your cannabis and hemp purifications and analysis. We are happy to discuss your applications and assist you in configuring the best technique and system to meet your chromatography needs.

Advantages:

• FLASH 50 and FLASH 250 can do both FLASH Chromatography and traditional HPLC on the same system
• HPLC backpressure capability to handle flash columns and preparative HPLC columns
• FAST (In a FLASH)
• Ability to use either normal or reverse phase
• Can use bonded phases to modify elution profiles
• Versatile
• High flow rates like traditional HPLC
• Proven and reliable

Uses:

• Any traditional HPLC application
• Purification of natural products (vitamins, vegetable dyes, dietary supplements)
• Isolation and purification of pharmaceutical drugs
• Isolation and purification of cannabinoids (cannabis and hemp)
• Isolation and purification of cannabinoids for use in edible products
• A preparative HPLC that can be used for any preparative HPLC techniques

The post FLASH 250- Integrated  Preparative Chromatography- FLASH appeared first on Icon Scientific Inc..

High efficiency COMPACT Preparative Chromatography System.

• 4 Channel 
• Scanning 
• 200-800
• 50 ml/min
• 4,351 psi

System includes:

• UV-Vis DAD detector 
• Preparative gradient pump
• Automatic injection valve
• Fraction collector 

The FLASH 50 Detector 

• Measures four (4) wavelengths simultaneously 
• Spectral scanning
• Can handle 10-30 millimeter diameter ID columns 

Flash Chromatography is a purification technique not an analytical tool like HPLC or UHPLC. Flash has been around for decades and was primarily used for pharmaceutical drug discovery R & D. Flash chromatography was used when a medicinal or organic chemist synthesized a new drug molecule. Before the chemist could study the compound of interest, they needed to purify or “clean up” the compound. The crude reaction mixture passes through a flash chromatography column in a “flash”. The pure drug compound is then isolated by selective elution. Flash Chromatography is a very effective purification technique and is still considered the primary purification technique used in R & D for the Pharmaceutical industry today.

Flash Chromatography is a type of preparative liquid chromatography. Flash Chromatography may be referred to as column chromatography or medium pressure Chromatography. Flash Chromatography is a special type of column chromatography. The FLASH 50 and FLASH 250 are capable of doing both preparative Flash Chromatography and preparative HPLC on the same system. Flash Chromatography is a preparative liquid chromatography method that easily and quickly separates organic compounds.

In chemistry, column chromatography is a chromatography method that is used to isolate a single chemical compound from a mixture. Flash Chromatography does just that, it purifies individual chemical compounds from a mixture of compounds. Flash Chromatography is most commonly used in the pharmaceutical industry for drug discovery, peptide and antibiotic purification, sample clean-up, early stage drug discovery, protein analysis, natural product analysis and more recently cannabis and hemp analysis.

Column chromatography techniques are implemented to separate steroids, hormones, vitamins alkaloids, cannabis and hemp. Column chromatography is also used to determine the amounts of those substances in samples of body fluids. Therefore, Flash Chromatography is an efficient method of extracting and purifying cannabis and hemp. There is an overwhelming need for a higher purity products. These techniques isolate cannabinoids and can further purify extracted cannabis raw materials.

Even though Flash Chromatography is a “medium pressure chromatography” both the FLASH 50 and the FLASH 250 systems can handle up to 4,351 psi. Flash Chromatography is a rapid method of column chromatography. It is called “flash” because it is a rapid method of column chromatography. Flash chromatography is high resolution chromatography. The solvent is pumped through a packed column at high flow rates. The sample loading capacity impacts yield and purity. While higher loads improve yield, they may diminish purity and lower loads may improve purity but possibly reduce yield.

Flash Chromatography is a very successful technique for those needing to purify cannabis and hemp extracts in order to remove impurities and isolate or separate individual cannabinoids. Flash Chromatography is also being used to isolate and purify cannabinoids for use in edible products.

An automated purification system includes a UV/VIS DAD Detector, a preparative gradient pump, automatic injection valve and a fraction collector. All of these components are controlled by a touch panel. There are two Flash Chromatography modes, normal-phase and reverse-phase. The phases have different separation mechanisms depending on your purification goals. Normal phase works well when separating compounds with significantly different polarities. It is often used to remove unwanted co-extractants and polar co-extracted impurities.

Flash Chromatography can be used as the front end of a CPC (Centrifugal Partition Chromatography) system. The cannabis and hemp processing industry needs to purify cannabis and hemp extracts in order to remove impurities an isolate/ separate individual cannabinoids. Flash Chromatography is one of the most successful methods used to achieve accurate, fast results. Icon Scientific offers many solutions to improve your cannabis and hemp purifications and analysis. We are happy to discuss your applications and assist you in configuring the best technique and system to meet your chromatography needs.

Advantages:

• FLASH 50 and FLASH 250 can do both FLASH Chromatography and traditional HPLC on the same system
• HPLC backpressure capability to handle flash columns and preparative HPLC columns
• FAST (In a FLASH)
• Ability to use either normal or reverse phase
• Can use bonded phases to modify elution profiles
• Versatile
• High flow rates like traditional HPLC
• Proven and reliable

Uses:

• Any traditional HPLC application
• Purification of natural products (vitamins, vegetable dyes, dietary supplements)
• Isolation and purification of pharmaceutical drugs
• Isolation and purification of cannabinoids (cannabis and hemp)
• Isolation and purification of cannabinoids for use in edible products
• A preparative HPLC that can be used for any preparative HPLC techniques

The post FLASH 50- Integrated Preparative Chromatography appeared first on Icon Scientific Inc..

Aflatoxins are the best known group of mycotoxins produced as secondary metabolites by fungi, mainly by Aspergillus flavus and Aspergillus parasiticus, but to a smaller extent also by other strains. This origin is also where the name Aspergillus flavus toxin comes from. Aflatoxins can be produced on crops in the field or during storage of agricultural products, especially under warm conditions and high humidity. Unfortunately, these substances can persist long after the fungi have been killed and therewith contaminate foods. Most mycotoxins are stable compounds that are also not destroyed during food processing or cooking.

Since they can easily enter the marketplace and be a hazard to public health it is important to develop effective analytical methods for the identification and quantification of mycotoxins. Governmental institutions and health protection agencies apply these methods on a large scale to control marketed food products and animal feed. In the food processing industry the same methods are used to check raw materials and products, in order to direct them to countries with an appropriate legislation.

The “AZURA® Aflatoxin System“ includes:

• AZURA Autosampler AS 6.1L for automatted sample injection
• AZURA Pump P 6.1L low pressure gradient pump with maximum pressure of 700 bar
• AZURA Column thermostat  CT 2.1 for column tempering and reproducible results
• Fluorescence detector RF-20A coupled to a photochemical postcolumn derivatization reactor for sensitive detection of aflatoxins
• Sample preparation kit consisting of SPE cartridges and method protocol
• Application description including method and analytical HPLC column

The system is controled with ClarityChrom® software. Additionally, a tablet PC with AZURA Mobile Control to monitor the system status and for direct control can be used.

Technical Data

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Carbohydrates, alcohols, and organic acids are important in the manufacture of many foods, pharmaceuticals, and biofuels. This dedicated system is specially designed to separate and analyze these compounds. The heart of this system is the superior AZURA refractive index detector RID 2.1L with an outstanding linear range and sensitivity. More systems components are the column thermostat CT 2.1 and the isocratic AZURA pump P 6.1L for delivery of small flow rates (0.001 -10 ml/min) and pressure up to 700 bar. This price attractive system is developed to run simple and rapid methods that enable simultaneous determination of sugars, organic acids and alcohols. Therefore, an interesting application is the analysis of all major wine compounds (see our application note) for quality control.

Technical Data

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The AZURA Compact HPLC isocratic educational system is a small complete analytical isocratic HPLC system. Due to its compact dimensions, the system fits onto every laboratory bench. The AZURA Compact HPLC isocratic is based on the multifunctional AZURA element ASM 2.1L and contains two integrated modules and a manual injecton valve, that is fixed to the side of the system. The integrated modules are a pump and a UV/VIS detector with one variable wavelength. A flow cell is included in the package. The system comes with an eluent tray for safe storage of up to six bottles. The column can be attached anywhere to the system via magnetic clip. A leak sensor and the capillary guidance as well as the optional

AZURA Mobile Control facilitate the safe and user friendly operation. The stackable elements of AZURA allow to create complex system solutions requiring a only minimum of space. Modern design with completely demountable fronts turn the system into a visual highlight.

Key Features

• Complete isocratic analytical HPLC system that needs very little bench space
• UV/VIS detector with one variable wavelength
• Pump unit with pressure sensor for a low pulsation eluent supply
• Optional AZURA Mobile Control App allows direct control of all integrated modules
• Leakage protection
• Complete software package ClarityChrom® (Educational Licence)
• Notebook
• Capillary scheme
• Application note
• Introduction to operation of software and hardware via short movies

Technical Data

The post AZURA Educational system appeared first on Icon Scientific Inc..

This system features a AZURA P 6.1L HPG/LPG pump, an Autosampler 6.1L, a column thermostat CT 2.1, a MWD or DAD 2.1L UV/VIS detector with 8-variable UV measuring channels from 190 – 750 nm, as well as a Tablet PC with AZURA Mobile Control. It is the standard system with a backpressure range of 700 bar. It perfectly fits the demanding needs of a method development system, as well as the robust fitness of a routine analysis machine.

The P6.1L with a HPG configuration features a solvent selection valve to set up to 4 solvents to the system of which two can be blended simultaneously. The internal degassing unit will prevent air bubbles in the system. Every P 6.1L comes with an attached mixing chamber, which can be changed to a larger volume depending on the applications needs.

The DAD 2.1L features a novel light path and flow cell architecture with improved handling and excellent performance. The frontal lamp and cell change ensures easy and secure maintenance. The temperature controlled optical bench minimizes signal drift. The wide flow cell selection allows the DAD 2.1L to be easily adapted to your needs.

The Autosampler 6.1L can inject 0.1 – 5000 µl to have a large flexibility. Using standard vials or two microtiter plates will give you a maximum sample capacity of up to 768 samples or 108 vials.

The AZURA CT 2.1 is the new price attractive basic column thermostat. It is suitable for column thermostatization above and below room temperature. The instrument operates with a microprocessor controlled Peltier element for exact temperature settings.

Key Features

• Complete gradient analytical HPLC system
• Variable multichannel UV/VIS Detector (or DAD)
• Pump unit with pressure sensor for a low pulsation eluent supply (max. 700 bar)
• AZURA Mobile Control unit allows direct control of all integrated modules
• Introduction to operation of software and hardware via short movies
• Complete software package ClarityChrom®
• Leakage protection
• PC with Monitor
• Tubing scheme
• Application note

Technical Data

The post AZURA HPLC Plus System appeared first on Icon Scientific Inc..

This system features a AZURA P 6.1L HPG/LPG pump, an Autosampler 6.1L, a column thermostat CT 2.1, a UVD 2.1L UV/VIS detector with 1-variable UV measuring channels from 190 – 750 nm, as well as a Tablet PC with AZURA Mobile Control. It is the standard system with a backpressure range of 700 bar. It perfectly fits the demanding needs of a method development system, as well as the robust fitness of a routine analysis machine.

The P6.1L with a HPG configuration features a solvent selection valve to set up up to 4 solvents to the system of which two can be blended simultaneously. The internal degassing unit will prevent air bubbles in the system. Every P 6.1L comes with an attached mixing chamber, which can be changed to a larger volume depending on the applications needs.

The UVD 2.1L comes with an installed deuterium lamp which covers a wavelength range from 190 to 750 nm. It is a competitively priced HPLC for routine HPLC applications including fast LC methods.

The Autosampler 6.1L can inject 0.1 – 5000 µl to have a large flexibility. Using standard vials or two microtiter plates will give you a maximum sample capacity of up to 768 samples or 108 vials.

The AZURA CT 2.1 is suitable for column thermostatization above and below room temperature. The instrument operates with a microprocessor controlled Peltier element for exact temperature settings.

Key Features

• Complete gradient analytical HPLC system
• Variable single wavelength 1-channel UV/VIS Detector
• Pump unit with pressure sensor for a low pulsation eluent supply (max. 700 bar)
• AZURA Mobile Control unit allows direct control of all integrated modules
• Complete software package ClarityChrom®
• Leakage protection
• PC with Monitor
• Tubing scheme
• Application note

Technical Data

The post AZURA HPLC Plus System appeared first on Icon Scientific Inc..

This system features a AZURA P 6.1L HPG/LPG pump, an Autosampler 6.1L, a column thermostat CT 2.1, a UVD 2.1L UV/VIS detector with 1-variable UV measuring channels from 190 – 750 nm, as well as a Tablet PC with AZURA Mobile Control. It is the standard system with a backpressure range of 700 bar. It perfectly fits the demanding needs of a method development system, as well as the robust fitness of a routine analysis machine.

The P6.1L with a LPG configuration features a new LPG valve for the most reise blending effciency. The internal degassing unit will prevent air bubbles in the system. Every P 6.1L comes with an attached mixing chamber, which can be changed to a larger volume depending on the applications needs.

The UVD 2.1L comes with an installed deuterium lamp which covers a wavelength range from 190 to 750 nm. It is a competitively priced HPLC for routine HPLC applications including fast LC methods.

The Autosampler 6.1L can inject 0.1 – 5000 µl to have a large flexibility. Using standard vials or two microtiter plates will give you a maximum sample capacity of up to 768 samples or 108 vials.

The AZURA CT 2.1 is suitable for column thermostatization above and below room temperature. The instrument operates with a microprocessor controlled Peltier element for exact temperature settings.

Key Features

• Complete gradient analytical HPLC system
• Variable single wavelength 1-channel UV/VIS Detector
• Pump unit with pressure sensor for a low pulsation eluent supply (max. 700 bar)
• AZURA Mobile Control unit allows direct control of all integrated modules
• Complete software package ClarityChrom
• Leakage protection
• PC with Monitor
• Tubing scheme
• Application note

Technical Data

The post AZURA HPLC Plus System appeared first on Icon Scientific Inc..

The AZURA® HPLC Compact iso is a small complete analytical isocratic HPLC system. Due to its compact dimensions, the system fits onto every laboratory bench.
The system is based on the multifunctional AZURA® Assistant ASM 2.1L and contains three integrated modules. An AZURA® Detector UVD 2.1S, an AZURA® Pump P 4.1S and a electric injection valve.

The system comes with an eluent tray for safe storage of up to 6 bottles. A leak sensor and the tubing guidance as well as the Mobile Control unit with touch screen, facilitate the safe and user friendly usage. Modern design with completely demountable fronts turn the system into a visual highlight.

The column thermostat AZURA® CT 2.1 is suitable for column thermostatization above and below room temperature.
The instrument operates with a microprocessor controlled Peltier element for exact temperature settings.

Key Features

• Complete isocratic analytical HPLC system that needs very little bench space
• UV/VIS detector with one variable wavelength
• RI detection with temperature controlled optical bench
• Pump unit with pressure sensor for a low pulsation eluent supply (max. 400 bar)
• Mobile Control unit allows direct control and data recording of all integrated modules
• Complete software package Mobile Control
• PC with monitor and ClarityChrom® software
• Tubing scheme
• Leakage protection

Technical Data

The post AZURA HPLC Compact isocratic (with UV and RI detection) appeared first on Icon Scientific Inc..

The AZURA® HPLC Compact iso is a small complete analytical isocratic HPLC system. Due to its compact dimensions, the system fits onto every laboratory bench.
The system is based on the multifunctional AZURA® Assistant ASM 2.1L and contains three integrated modules; an AZURA® Detector UVD 2.1S, an AZURA® Pump P 4.1S and a electric injection valve

The system comes with an eluent tray for safe storage of up to 6 bottles. The column can be attached anywhere to the system via magnetic clip. A leak sensor and the tubing guidance as well as the Mobile Control unit with touch screen, ensure the safe and user friendly usage. Modern design with completely demountable fronts turn the system into a visual highlight.

Key Features

• Complete isocratic analytical HPLC system that needs very little bench space
• UV/VIS detector with one variable wavelength
• Pump unit with pressure sensor for a low pulsation eluent supply (max. 400 bar)
• Mobile Control Chrom allows direct control and data recording of all integrated modules
• Leakage protection
• Complete software package Mobile Control
• Tubing scheme

Technical Data

The post AZURA HPLC Compact isocratic (with UV detection) appeared first on Icon Scientific Inc..

This system features a AZURA P 6.1L HPG/LPG pump, an Autosampler 6.1L, a column thermostat CT 2.1, a MWD or DAD 2.1L UV/VIS detector with 8-variable UV measuring channels from 190 – 750 nm, as well as a Tablet PC with AZURA Mobile Control. It is the standard system with a backpressure range of 700 bar. It perfectly fits the demanding needs of a method development system, as well as the robust fitness of a routine analysis machine.

The P6.1L with a LPG configuration features a new LPG valve for the most reise blending effciency. The internal degassing unit will prevent air bubbles in the system. Every P 6.1L comes with an attached mixing chamber, which can be changed to a larger volume depending on the applications needs.

The DAD 2.1L features a novel light path and flow cell architecture with improved handling and excellent performance. The frontal lamp and cell change ensures easy and secure maintenance. The temperature controlled optical bench minimizes signal drift. The wide flow cell selection allows the DAD 2.1L to be easily adapted to your needs.

The Autosampler 6.1L can inject 0.1 – 5000 µl to have a large flexibility. Using standard vials or two microtiter plates will give you a maximum sample capacity of up to 768 samples or 108 vials.

The AZURA CT 2.1 is the new price attractive basic column thermostat. It is suitable for column thermostatization above and below room temperature. The instrument operates with a microprocessor controlled Peltier element for exact temperature settings.

Key Features

• Complete gradient analytical HPLC system
• Variable multichannel UV/VIS Detector (or DAD)
• Pump unit with pressure sensor for a low pulsation eluent supply (max. 700 bar)
• AZURA Mobile Control unit allows direct control of all integrated modules
• Complete software package ClarityChrom®
• Leakage protection
• PC with Monitor
• Tubing scheme
• Application note

Technical Data

The post AZURA HPLC Plus System appeared first on Icon Scientific Inc..

This system features a AZURA P 6.1L HPG pump, an Autosampler 6.1L, a column thermostat CT 2.1, a DAD 6.1L UV/VIS detector with 8-variable UV measuring channels from 190 – 1000 nm, as well as a Tablet PC with AZURA Mobile Control. It is the UHPLC system with a backpressure range of 1000 bar. It perfectly fits the demanding needs of a method development system, as well as the robust fitness of a routine analysis machine.

The P6.1L with a LPG configuration features a new LPG valve for the most precise blending effciency. The internal degassing unit will prevent air bubbles in the system. Every P 6.1L comes with an attached mixing chamber, which can be changed to a larger volume depending on the applications needs.

The DAD 6.1L features a novel light path and flow cell architecture with improved handling and excellent performance. The frontal lamp and cell change ensures easy and secure maintenance. The temperature controlled optical bench minimizes signal drift. The wide flow cell selection allows the DAD 6.1L to be easily adapted to your needs..

The Autosampler 6.1L can inject 0.1 – 5000 µl to have a large flexibility. Using standard vials or two microtiter plates will give you a maximum sample capacity of up to 768 samples or 108 vials.

The AZURA CT 2.1 is the new price attractive basic column thermostat. It is suitable for column thermostatization above and below room temperature. The instrument operates with a microprocessor controlled Peltier element for exact temperature settings

Key features

• Complete gradient analytical HPLC system
• Variable multichannel UV/VIS Detector (or DAD)
• Pump unit with pressure sensor for a low pulsation eluent supply (max. 1000 bar)
• AZURA Mobile Control unit allows direct control of all integrated modules
• Introduction to operation of software and hardware
• Complete software package OpenLAB
• Mobile Control for maintenance and diagnostics
• Leakage protection
• PC with Monitor

Technical Data

The post AZURA UHPLC System appeared first on Icon Scientific Inc..

This system features a AZURA P 6.1L HPG pump, an Autosampler 6.1L, a column thermostat CT 2.1, a DAD 6.1L UV/VIS detector with 8-variable UV measuring channels from 190 – 1000 nm, as well as a Tablet PC with AZURA Mobile Control. It is the UHPLC system with a backpressure range of 1000 bar. It perfectly fits the demanding needs of a method development system, as well as the robust fitness of a routine analysis machine.

The P6.1L with a HPG configuration features a solvent selection valve to set up to 4 solvents to the system of which two can be blended simultaneously. The internal degassing unit will prevent air bubbles in the system. Every P 6.1L comes with an attached mixing chamber, which can be changed to a larger volume depending on the applications needs.

The DAD 6.1L features a novel light path and flow cell architecture with improved handling and excellent performance. The frontal lamp and cell change ensures easy and secure maintenance. The temperature controlled optical bench minimizes signal drift. The wide flow cell selection allows the DAD 6.1L to be easily adapted to your needs..

The Autosampler 6.1L can inject 0.1 – 5000 µl to have a large flexibility. Using standard vials or two microtiter plates will give you a maximum sample capacity of up to 768 samples or 108 vials.

The AZURA CT 2.1 is the new price attractive basic column thermostat. It is suitable for column thermostatization above and below room temperature. The instrument operates with a microprocessor controlled Peltier element for exact temperature settings

Key features

• Complete gradient analytical HPLC system
• Variable multichannel UV/VIS Detector (or DAD)
• Pump unit with pressure sensor for a low pulsation eluent supply (max. 1000 bar)
• AZURA Mobile Control unit allows direct control of all integrated modules
• Introduction to operation of software and hardware
• Complete software package OpenLAB
• Mobile Control for maintenance and diagnostics
• Leakage protection
• PC with Monitor

Technical Data

The post AZURA UHPLC System appeared first on Icon Scientific Inc..

This very compact system is specially designed to separate different natural components, like carbohydrates, alcohols and organic acids. It is optimized for the separation of several hundred mg to gram per day.

System components

The heart of the system is the superior AZURA refractive index detector RID 2.1L HighFlow with an outstanding linear range and sensitivity. The intelligently designed optical unit with advanced temperature control ensures high sensitivity, fast baseline stabilization, and excellent reproducibility. The wide linear dynamic range and 100 ml/min maximum flow rate make the AZURA RID 2.1L HighFlow the perfect choice for most laboratory tasks and it is an excellent device for semi-preparative purification of sugars using the KNAUER Eurokat columns. The other systems component is the AZURA Assistent ASM 2.1L. This sugar purification assistent combines the functionality of two different devices, a pump and a valve. The isocratic AZURA Pump P 4.1S can work with flow rates up to 50 ml/min and a maximum pressure of 150 bar. The 12 port multi-position valve AWA20BG for fractionation is made of stainless steel and has a maximum flow rate of 500 ml/min. This price attractive system is made in Germany and fulfills the highest quality standards. To see the power of the compact AZURA system, take a look at our application where we purified xylittol from fermentation mash.

Technical Data

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Do not waste time and labor with manual sample preparation. The AZURA® GPC Cleanup system automates work-intensive and time-consuming cleanup tasks based on gel permeation chromatography (GPC). Further, reproducibility and quality of the cleanup are improved. After sample loading, the dedicated system fully automatically processes up to 15 samples while requiring minimal bench space. Based on the versatile AZURA® device platform the system can be customized to fulfill individual requirements. The cost-effective software Mobile Control provides a touch-optimized user interface for intuitive device control directly at the system.

System layout
Based on the versatile AZURA® device platform the GPC Cleanup System can be easily adapted to pre-established laboratory procedures to perform a wide range of sample preparation tasks. The required bench space is kept at a minimum. Scroll down to “Related Products” to find alternative system components for customization.
The system features 15 sample loops controlled by two 16 port multiposition valves. The GPC tubing guide sorts outlet tubings coming from the fraction collection valve. The wound-up sample loops are stored in a tray with drainage system and are easily accessible for inspection and replacement. With an additional multiposition valve 15 fractions and waste can be collected. All multiposition valves and the manual injection valve are integrated into a compact AZURA® Assistant ASM 2.1L. Elution of separated substances/standard components is monitored by a variable single wavelength UV detector. A second assistant harbors the small detector, the system pump with a pressure sensor and a valve to bypass the GPC column or select between two columns.

System control
The GPC Cleanup System is operated with the cost-effective software Mobile Control. This clearly arranged and touch-optimized user interface is run on a tablet directly mounted at the system. It automatically recognizes devices and the system is configured within a few finger swipes. Due to the arrangement in functional blocks like eluent delivery, sample injection, detection, fraction collection, programs are created fast with a minimal number of clicks. Mobile Control makes sample loop loading easily manageable by synchronously switching both valves at the push of a button. Download Mobile Control Chrom!

What is GPC Cleanup?
GPC Cleanup (Gel Permeation Chromatography) is primarily employed for performing general cleanup tasks on a wide range of sample matrices such as foodstuffs, tissues, plants and environmental samples. The separation of components takes place according to their molecular weight due to the heterogeneous pore size of the stationary phase which acts as a molecular sieve. High-molecular substances such as lipids, proteins, natural resins, cellular components and steroids interfering with subsequent analysis e.g. of pesticides are efficiently removed.

In accordance with established methods to determine pesticide residues

• Method 984.21 – AOAC international
• EPA SW-846 Method 3640A – US Environmental Protection Agency
• AEN 12393 and EN 1528 – European Standard
• L 00.00-34 Method in accordance with §64 LFGB (formerly § 35 LMBG)

The AZURA® GPC Cleanup system was selected by the Analytical Scientist for “The Innovators 2017” product. Click here to read the full article.

The GPC Cleanup System is also covered in the poster “Automated sample preparation with touch-optimized control software”. Check the dowloads below.

Technical Data

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The 3D option enables the acquisition and analysis of 3D data with diode-array detectors. The DAD license requires the full version of PurityChrom.

Technical Data

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