Degassers – Icon Scientific Inc. https://www.iconsci.com Highest Quality Liquid Chromatography Products & Service Fri, 07 Feb 2025 20:19:57 +0000 en-US hourly 1 https://wordpress.org/?v=6.9.4 https://www.iconsci.com/wp-content/uploads/2019/03/favicon.png Degassers – Icon Scientific Inc. https://www.iconsci.com 32 32 iPlanar Degasser – 530D4 https://www.iconsci.com/shop/iplanar-530d4/ Wed, 17 Aug 2022 17:15:43 +0000 https://www.iconsci.com/?post_type=product&p=4789 Degasser channels 4 Max. flow rate/channel 30 ml/min Recommended flow rate/channel 10 ml/min Degassing method Gas permeation through dual thin […]

The post iPlanar Degasser – 530D4 appeared first on Icon Scientific Inc..

]]>
Degasser channels 4
Max. flow rate/channel 30 ml/min
Recommended flow rate/channel 10 ml/min
Degassing method Gas permeation through dual thin film teflon AF TM membranes
Degassing chamber volume 530 µl
Wetted materials teflon AF TM, PEEK
Internal fittings None
Display Touch Screen
Liquid Connections

 1/4-28 flat bottom ports
Average pressure drop

 Less than 3 mbar (with vacuum applied)
Dimensions

3 3/4″ x  10 1/2″ x 6″

9 1/2 cm x 27 cm x 15cm
Weight

3 Lbs 5oz

1.5 kg
Model # 530D4
Part # IC530D4

The post iPlanar Degasser – 530D4 appeared first on Icon Scientific Inc..

]]> iPlanar Degasser – 530D2 https://www.iconsci.com/shop/iplanar-degasser-530d2/ Wed, 17 Aug 2022 17:13:34 +0000 https://www.iconsci.com/?post_type=product&p=4788 Degasser channels 2 Max. flow rate/channel 30 ml/min Recommended flow rate/channel 10 ml/min Degassing method Gas permeation through dual thin […]

The post iPlanar Degasser – 530D2 appeared first on Icon Scientific Inc..

]]>
Degasser channels 2
Max. flow rate/channel 30 ml/min
Recommended flow rate/channel 10 ml/min
Degassing method Gas permeation through dual thin film teflon AF TM membranes
Degassing chamber volume 5300 µl
Wetted materials teflon AF TM, PEEK
Internal fittings None
Display Touch Screen
Liquid Connections

 1/4-28 flat bottom ports
Average pressure drop

 Less than 3 mbar (with vacuum applied)
Dimensions

3 3/4″ x  10 1/2″ x 6″

9 1/2 cm x 27 cm x 15cm
Weight

3 Lbs 1oz

1.4 kg
Model # 530D2
Part # IC530D2

The post iPlanar Degasser – 530D2 appeared first on Icon Scientific Inc..

]]> iPlanar Degasser – 320D4 https://www.iconsci.com/shop/iplanar-degasser-320d4/ Wed, 17 Aug 2022 17:10:33 +0000 https://www.iconsci.com/?post_type=product&p=4787 Degasser channels 4 Max. flow rate/channel 10 ml/min Recommended flow rate/channel 5 ml/min Degassing method Gas permeation through dual thin […]

The post iPlanar Degasser – 320D4 appeared first on Icon Scientific Inc..

]]>
Degasser channels 4
Max. flow rate/channel 10 ml/min
Recommended flow rate/channel 5 ml/min
Degassing method Gas permeation through dual thin film teflon AF TM membranes
Degassing chamber volume 320 µl
Wetted materials teflon AF TM, PEEK
Internal fittings None
Display Touch Screen
Liquid Connections

 1/4-28 flat bottom ports
Average pressure drop

 Less than 3 mbar (with vacuum applied)
Dimensions

3 3/4″ x  10 1/2″ x 6″

9 1/2 cm x 27 cm x 15cm
Weight

3 Lbs 5oz

1.5 kg
Model # 320D4
Part # IC320D4

The post iPlanar Degasser – 320D4 appeared first on Icon Scientific Inc..

]]> iPlanar Degasser – 320D2 https://www.iconsci.com/shop/iplanar-degasser-320d2/ Wed, 17 Aug 2022 16:52:27 +0000 https://www.iconsci.com/?post_type=product&p=4785 Degasser channels 2 Max. flow rate/channel 10 ml/min Recommended flow rate/channel 5 ml/min Degassing method Gas permeation through dual thin […]

The post iPlanar Degasser – 320D2 appeared first on Icon Scientific Inc..

]]>
Degasser channels 2
Max. flow rate/channel 10 ml/min
Recommended flow rate/channel 5 ml/min
Degassing method Gas permeation through dual thin film teflon AF TM membranes
Degassing chamber volume 320 µl
Wetted materials teflon AF TM, PEEK
Internal fittings None
Display Touch Screen
Liquid Connections

 1/4-28 flat bottom ports
Average pressure drop

 Less than 3 mbar (with vacuum applied)
Dimensions

3 3/4″ x  10 1/2″ x 6″

9 1/2 cm x 27 cm x 15cm
Weight

3 Lbs 1oz

1.4 kg
Model # 320D2
Part # IC320D2

The post iPlanar Degasser – 320D2 appeared first on Icon Scientific Inc..

]]> Preparative 4 channel Degasser https://www.iconsci.com/shop/preparative-4-channel-degasser/ Thu, 18 Jun 2020 15:33:36 +0000 https://www.iconsci.com/?post_type=product&p=4455 Preparative 4 channel degasser, biocompatible

The post Preparative 4 channel Degasser appeared first on Icon Scientific Inc..

]]>

Degasser module

Degasser channels 4
Max. flow rate/channel 200 ml/min
Recommended flow rate/channel 75
Degassing method Gas permeation through a fluoropolymer membrane
Degassing chamber volume 23 ml
Solvent applicability Not to be used with HFIP. Compatible with hexane, heptane, THF, dichloromethane and ethylacetate.
Wetted materials Systec AF TM, FEP, PPS, PTFE, Tefzel® (ETFC)
Maximum pressure stability 50 psi

Technical parameters

Conformity 1/4″-28 UNF Female Port

The post Preparative 4 channel Degasser appeared first on Icon Scientific Inc..

]]> Preparative 2 channel Degasser https://www.iconsci.com/shop/preparative-2-channel-degasser/ Thu, 18 Jun 2020 15:31:50 +0000 https://www.iconsci.com/?post_type=product&p=4454 Preparative 2 channel degasser, biocompatible

The post Preparative 2 channel Degasser appeared first on Icon Scientific Inc..

]]>

Degasser module

Degasser channels 2
Max. flow rate/channel 200 ml/min
Recommended flow rate/channel 75 ml/min
Degassing method Gas permeation through a fluoropolymer membrane
Degassing chamber volume 23 ml
Solvent applicability Not to be used with HFIP. Compatible with hexane, heptane, THF, dichloromethane and ethylacetate.
Wetted materials FEP, PPS, PTFE, Systec AF TM, Tefzel® (ETFC)
Maximum pressure stability 50 psi

Technical parameters

Conformity 1/4″-28 UNF Female Port

General

Power supply 100-240V AC 1A 50 – 60hz
Dimensions 260 x 110 x 150 mm

The post Preparative 2 channel Degasser appeared first on Icon Scientific Inc..

]]> Analytical 4 channel degasser https://www.iconsci.com/shop/analytical-4-channel-degasser/ Thu, 18 Jun 2020 15:30:24 +0000 https://www.iconsci.com/?post_type=product&p=4453 Degasser module Degasser channels 4 Max. flow rate/channel 10 ml/min Recommended flow rate/channel 2 ml/min Degassing method Gas permeation through […]

The post Analytical 4 channel degasser appeared first on Icon Scientific Inc..

]]>

Degasser module

Degasser channels 4
Max. flow rate/channel 10 ml/min
Recommended flow rate/channel 2 ml/min
Degassing method Gas permeation through a fluoropolymer tube membrane
Degassing chamber volume 285 µl
Wetted materials Systec AF TM, PPS, PEEK, PTFE
Maximum pressure stability 70 psi
Display Single bi-color LED

 

Technical Parameters

Conformity 1/4″-28 UNF Female Port

General

Power supply 100-240V AC 1A 50 to 60hz
Dimensions 167 x 107 x 56 mm

The post Analytical 4 channel degasser appeared first on Icon Scientific Inc..

]]> AZURA DG 2.1S https://www.iconsci.com/shop/azura-dg-2-1s/ Thu, 18 Jun 2020 15:27:46 +0000 https://www.iconsci.com/?post_type=product&p=4451 Biocompatible 2 channel degasser

Dissolved gases in the solvent can cause bubbles in the flow path of pumps and detectors. Reliable chromatographic separation therefore requires degassing of the solvent. The small analytical 2-channel degasser DG 2.1S is equipped with two degassing chambers and can thus degas two solvents simultaneously.

The post AZURA DG 2.1S appeared first on Icon Scientific Inc..

]]> The post AZURA DG 2.1S appeared first on Icon Scientific Inc..

]]> Accessory kit AZURA DG 2.1S https://www.iconsci.com/shop/accessorykitazuradg21s/ Fri, 24 Aug 2018 11:43:00 +0000 https://www.iconsci.com/products/accessorykitazuradg21s/ Included in shipkit

The post Accessory kit AZURA DG 2.1S appeared first on Icon Scientific Inc..

]]> This accessory kit is included in the shipkit of AZE02 (DG 2.1S).

  • A0732: PTFE tubing, 3.2 mm (1/8″) OD, 1.5 mm ID, 300 cm length
  • 2x A1149: PTFE solvent filter, tubing included
  • 4x M0689: Flangeless Fittings 1/8″, blue PEEK
  • M1057: Flangless Ferrule 1/8” Tefzel, 10 pcs
  • 2x P2738: Bushing 1/8″

The post Accessory kit AZURA DG 2.1S appeared first on Icon Scientific Inc..

]]> AZURA DG 2.1S module for ASM 2.1L https://www.iconsci.com/shop/azuradg21smoduleforasm21l/ Fri, 24 Aug 2018 11:29:00 +0000 https://www.iconsci.com/products/azuradg21smoduleforasm21l/ Semiprep 2-channel degasser, suitable for biocompatible applications

The post AZURA DG 2.1S module for ASM 2.1L appeared first on Icon Scientific Inc..

]]> Dissolved gases in the solvent can cause bubbles in the flow path of pumps and detectors. Reliable chromatographic separation therefore requires degassing of the solvent. The semiprep 2-channel degasser DG 2.1S is equipped with two degassing chambers and can thus degas two solvents simultaneously. For integration into ASM 2.1L only. Not available as stand-alone device.

Key features

  • Degassing of up to two eluents simultaneously
  • Degasser nominal performance: 10 ml/min per channel
  • Small dead volume
Degasser channels

2
Degasser maximum flow rate

50 ml/min
Degassing method

gas permeation through a fluoropolymer membrane
Dead volume

approx. 925 µl per channel
Solvent applicability

universal, except hydrochloric acid and halogenated hydrocarbons especially hexafluoro isopropanol (HFIP), hexane, heptane
Pressure decline

1.37 mm (Hg /ml /min)
Maximum pressure stability

7 bar
Wetted materials

PEEK, glass-filled PTFE, Teflon AF®
Ambient conditions

temperature range: 4 – 40 °C, 39.2 – 104 °F

air humidity: below 90%, non-condensing

The post AZURA DG 2.1S module for ASM 2.1L appeared first on Icon Scientific Inc..

]]> Online Degasser https://www.iconsci.com/shop/onlinedegasser/ Fri, 24 Aug 2018 11:18:00 +0000 https://www.iconsci.com/products/onlinedegasser/ 2-channel, analytical, solvent resistant

The post Online Degasser appeared first on Icon Scientific Inc..

]]> Why is online degassing so important?

Online degassing is important when doing HPLC, FPLC, GPC, and uHPLC because degassing will remove dissolved gas therefore avoiding bubble formation. Degassing will improve quantitative analysis. Online degassing replaces helium sparging.

Outgassing is a term used to describe dissolved gases coming out of solution. This occurs in HPLC systems where rough surfaces produce nucleation sites for bubble formation. Bubbles entering the HPLC systems will present a false signal to the detector.

Outgassing and bubble formation create problems for HPLC, FPLC, GPC and uHPLC systems.

Low pressure mixing: systems are more prone to bubble formation. The solvents used for the mobile phase are mixed before the pump. Outgassing affects the volume of liquid after the valve and before the pump because the valves are proportioned based on time and cannot discern whether there are bubbles in the liquid or not. This results in an inaccurate gradient.

  • With high pressure mixing each solvent has its own pump and mixing takes place after the pumps. This configuration is less prone to outgassing issues.
  • Outgassing creates bubbles in the flow cell
  • Outgassing disrupts the column bed in FPLC ruining the separation process
  • Bubble formation can be the cause of many performance issues, both with low pressure and high-pressure mixing

Our online degasser modules use proprietary technology. A flat membrane is incorporated on both sides of the cassette to provide maximum surface area with minimal volume. We optimize the efficiency of the membrane by precisely controlling its thickness to maximize degassing efficiency. Vacuum degassing is optimized because the membrane has a high gas permeability, ensuring both efficient and continuous gas removal, regardless of the flow rates. This technology also enhances the lifetime of the degasser.  This innovative technique enables the highest degassing efficiency in the industry. Our breakthrough in technology hugely improves traditional Teflon tube degassers that are commonplace today.

We offer 2-8 channel modules that are available to handle analytical to semi-prep applications. All modules work with HPLC, UHPLC, FPLC, and GPC. Custom OEM configurations are available.

Outgassing occurs when gasses that have dissolved into the solvent or buffer cause bubbles in pumps and detectors. Therefore, good chromatographic separations require degassing the solvents or buffers.

While the solvent flows through the Teflon AF® membrane, the dissolved gases are removed from the solvent by means of a vacuum on the other side of the membrane. Typically 50% of dissolved gas must be removed from the solvent stream to avoid bubble formation. Online degassers are used at universities, research institutions, and laboratories in the following areas: biochemistry analysis, chemical analysis, pharmaceutical analysis, food and beverage analysis, environmental analysis, chiral analysis and protein purifications. Our degassers are engineered for superior performance and the highest degassing efficiency in the industry. We use Teflon AF® in all of our analytical and semi-prep degassers. The benefit of online degassing is that it is a continuous process as opposed to helium sparging which is typically done prior to the chromatographic run. After the solvents are helium sparged, gases are reintroduced into the solvent providing inconsistent degassing which degrades over time.

Read More

Why is it important to eliminate bubbles through online degassing?

  • Bubbles in the flow cell cause erroneous spikes in your chromatograms
  • Bubbles in solvents cause inaccurate and irreproducible gradient information
  • Bubbles in solvent steam create inaccurate flow rates causing changes in chromatographic retention times
  • Bubbles cause noisy baselines
  • When Dissolved gas forms bubbles they affect the accuracy, precision and performance of your chromatography system.

If gas dissolves in liquid it is likely to cause disturbances in fluidic systems. Gas molecules can form bubbles when pressure or temperature changes. Using our degassers optimizes the performance of HPLC, uHPLC and FPLC systems.

Degassers are the solution to air bubbles in the fluidic lines which cause problems and lead to production disruptions or delays.

Degassers improve reliability because they remove dissolved gases from fluids prior to outgassing. This prevents bubbles from forming and causing problems.

Benefits of using online degassing:

  • improves baseline stability
  • efficiently removes dissolved gases from fluid stream
  • prevents bubbles from forming
  • reduces noise
  • reduces start-up times
  • ensures more constant and accurate results

Degassers for HPLC systems: Analytical degassers are degassers used for this degassing solvent in HPLC and uHPLC systems.

Our analytical degassers include:

AZE 03-1- 4 channel degasser biocompatible

AZE 02-AZURA DG 2.1S- 2 channel degasser

A 5335- analytical 2 channel degasser for GPC

Semi-prep degassers are designed to handle flow rates up to 30 mls/min

Our Knauer semi-prep/degasser is an analytical 2 channel degasser for GPC. The model number is Smartline A 5328.

Preparative degasser- preparative degassers are used for higher flow pumping systems or chromatography systems that can handle flow rates up to 1000 mls/min.

Preparative degassers options are:

AZE 03 – Preparative 4 channel degasser

AZE 02-1 Preparative 2 channel degasser

 

The post Online Degasser appeared first on Icon Scientific Inc..

]]> Smartline Online degasser https://www.iconsci.com/shop/smartlineonlinedegasser/ Fri, 24 Aug 2018 11:11:00 +0000 https://www.iconsci.com/products/smartlineonlinedegasser/ The 2-channel degasser module provides outstanding performance through its use of a newly developed micro vacuum pump while taking up […]

The post Smartline Online degasser appeared first on Icon Scientific Inc..

]]> The 2-channel degasser module provides outstanding performance through its use of a newly developed micro vacuum pump while taking up only a minimum of space. The gas diffusion rate has been improved by a factor of 200 – 300 times, thanks to a new amorphous fluoropolymer rather than a regular Teflon membrane. Excellent chemical and physical stability parameters, as well as the reduction of the internal chamber volume to less than 8 ml are convincing features. The semi-preparative KNAUER online degasser module can be used for flow rates of up to 50 ml/min.

Degasser module
Degasser channels

2
Degasser maximum flow rate

up to 50 ml/min
Degassing method

gas permeation through Teflon® AF amorphous fluoropolymer membrane
Degassing efficiency

< 0.5 ppm dissolved O2at 1 ml/min
Degassing chamber volume

7.7 ml per chamber
Solvent applicability

universal, except hydrochloric acid and halogenated hydrocarbons especially hexafluoro isopropanol (HFIP), hexane, heptane
Wetted materials

PEEK, glass-filled PTFE, Teflon® AF
Vacuum pump

micro vacuum pump with step motor

> 6.2 kPa : 400 cycles/min

< 6.2 kPa : 60 cycles/min
Chamber material

polypropylene and stainless steel
Technical parameters
Ambient conditions

Ambient temperature: -20 to +60 ºC

Ambient Relative Humidity: 20 to 80 % RH (without condensation)
General
Power supply

85–265 V, 47–63 Hz, 20 W
Dimensions

85 x 165 x 315 mm (W x H x D)
Weight

2.5 kg

The post Smartline Online degasser appeared first on Icon Scientific Inc..

]]>